Endocrine Abstracts

Background: Graves’ disease (GD) is the commonest cause of primary hyperthyroidism in iodine-sufficient areas. First-line treatment is a 12-18 month course of anti-thyroid drugs (ATD). However, around 50% of GD patients will relapse, requiring further assessment and definitive treatment with radioactive iodine or thyroidectomy. Identifying risk factors that predict relapse or treatment failure after stopping ATD is important in guiding management. Several risk factors hav...

Introduction: Hypercalcemia has wide spectrum of diagnosis. Hyperthyroidism is known cause of parathyroid hormone independent cause of hypercalcemia. Increased osteoclast activity with excess bone resorption is underlying cause. Thyrotoxicosis associated hypercalcemia is usually asymptomatic, mild to moderate hypercalcemia is seen in 20% of patients, but severe hypercalcemia is rare. We report a case of young male who presented with abdominal pain, vomiting se...

Background: Graves’ disease (GD) is the commonest cause of primary hyperthyroidism. First-line treatment involves 12-18 months of anti-thyroid drugs (ATD). Subsequently, around 50% of patients will relapse, requiring definitive treatment. Identifying risk factors that predict relapse or treatment failure can guide management. We aimed to explore risk factors that identify patients at high risk of relapse or medical treatment failure, to allow prioritisati...